Most dog owners are familiar with joint supplement products that have glucosamine and chondroitin. The former is a connective tissue structural building unit, while the latter is specifically a cartilage structural building unit. Some have heard of MSM, a key sulfur source for the addition of sulfur to these compounds, a key component to conversion to their active “sulfated” forms. Some also have heard of the benefits of essential fatty acids for the natural increased production of joint fluid to increase joint lubrication, while naturally reducing inflammation by blocking biochemical inflammatory pathways.
Most canine owners have not, however, heard of the new and innovative powerful joint inflammation reducing properties of UC-II, boswellia serrata extract, astaxanthin, and bromelain. UC-II is a collagen extract that desensitizes the immune system and prevents immune attacks on joint, a key component to the progression of joint inflammation and osteoarthritis.
Boswellia serrata extract inhibits the pro-inflammatory enzymes COX-2 and LOX-5 that are key components to the joint inflammation cascade. Astaxanthin is a powerful antioxidant, 6000 more potent than Vitamin C and is also a COX-2 enzyme inhibitor. The potent antioxidant activity reduces oxidative stress on the body including the joints, while the inflammatory enzyme inhibition contributes to less inflammation. Finally, bromelain is an enzyme known for its anti-edema properties which effectively reduces swelling.
My animal hospital is currently working with the innovative pharmaceutical company, Ceva, to develop a joint chew product for dogs that combines the benefits of the well-established joint health supplement products discussed in the first paragraph, with these new cutting edge products to produce the most comprehensive and effective canine joint chew to date. This product will reduce doses and dependence on anti-inflammatory medications, serving to provide relief without the potential damage to the liver, kidneys, and gastrointestinal system these drugs can cause over time. We are only weeks away from product development, so stay tuned!
Dr. Roger Welton is the President of Maybeck Animal Hospital in West Melbourne, FL, Chief Editor of the Veterinary Advice and Information Website, Web-DVM, and founder/CEO of Dr. Roger’s Holistic Veterinary Care.